This text examines access to health care for patients suffering from rare diseases in Serbia, especially those living outside major urban centers. The focus of research is the introduction of a new entity in the healthcare system – Centers for Rare Diseases. Based on the analysis of the legal and strategic framework, as well as qualitative research, a number of problems in access to health and social care for people with rare diseases were observed. The paper presents a set of recommendations for solving the problem of access to services for all citizens.